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What does it do?

As you go through menopause, you produce less of the hormone oestrogen. MHT replaces this hormone. MHT tablets contain either only oestrogen, or both oestrogen and progestogen. Oestrogen treats symptoms of menopause and helps prevent weak bones (osteoporosis). Progestogen protects the lining of your uterus (womb) and reduces your chance of endometrial cancer. If you have had a hysterectomy (your uterus has been removed) then you only need to take oestrogen.

For more information see the Australasian Menopause Society.

Before you start

  • Women taking MHT may have a small increased chance of breast cancer, blood clots, and stroke. Tell your doctor if you, or someone in your family, has ever had any of these problems.
  • For most women, there is no increased chance of heart attacks. There may be a small increased chance if you are older than 60, or it has been over 10 years since menopause. Tell your doctor if you, or someone in your family, has ever had heart problems.

How should you take it?

Take MHT regularly as directed with a glass of water. You can take it with or without food.

What if you forget a dose?

If it is nearly time for your next dose, skip the missed dose and take your next dose at the usual time. Otherwise, take the missed dose as soon as you remember. Do not take two doses at the same time.

Can you take other medicines?

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products (e.g. St John's wort) or recreational drugs.

What side effects might you notice?

Side EffectsRecommended action

Symptoms of a blood clot including: sudden shortness of breath, swelling or pain in one leg

Symptoms of a stroke including: sudden weakness of the face, arm or leg, especially on one side, face drooping, sudden changes in vision or speech, sudden loss of balance

Tell your doctor immediately

Unexpected vaginal bleeding

Tell your doctor

Headache

Mood changes

Sore or enlarged breasts

Vaginal itch/discharge

Bloating, stomach upset, stomach cramps

Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • MHT does not protect against pregnancy. You can still get pregnant up to 1 year after your last period if you are older than 50, or up to 2 years if you are under 50. Talk to your doctor about contraception options.
  • MHT is also known as hormone replacement therapy (HRT).

This leaflet contains important, but not all, information about this medicine.

Prepared by the MyMedicines Committee at Christchurch Hospital, Te Whatu Ora - Waitaha, New Zealand. May 2026

For more general information about this sheet and its contents, see: What does a My Medicines sheet cover?

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About My Medicines

My Medicines Patient Information Leaflets (PILs) contain important, but not all, information about the medicines they describe.

For more information about the sheets, see: What does a My Medicines sheet cover?

My Medicines is developed by a team at Te Whatu Ora – Waitaha. Our team is made up of doctors, pharmacists, and a non-medical person to help us keep to plain language. We also discuss our information with specialist health professionals or groups when needed