NZ Formulary

Ritonavir

ri-to-na-veer

What does it do?

Ritonavir is used to control HIV.

Before you start

  • Tell your doctor if you have heart, liver, or kidney problems, diabetes, high cholesterol, or haemophilia.
  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

How should you take it?

Take ritonavir as directed with food. It is very important to take it regularly. If you often forget to take ritonavir, it may not work as well.
Take the tablets with a glass of water.
Measure the liquid carefully with an oral syringe or measuring spoon. Shake the bottle well before measuring each dose.

What if you forget a dose?

If it is nearly time for your next dose, skip the missed dose and take your next dose at the usual time. Otherwise, take the missed dose as soon as you remember. Do not take two doses at the same time.

Can you take other medicines?

Ritonavir can react with many medicines, sometimes with severe results.
Tell your pharmacist or doctor about all medicines or treatments that you may be taking including vitamins, herbal products, or recreational drugs.

Important information continues on next page.

What side effects might you notice?

Side EffectsRecommended action

Symptoms of allergy including: skin rash, itching, swelling, trouble breathing

Symptoms of liver problems including: yellow skin or eyes, itching, dark urine, pale bowel motions, abdominal pain

Severe stomach pain, nausea

Chest pain, fainting

Tell your doctor immediately

Peeing more often, feeling thirsty

Tell your doctor

Dizziness, headache, tiredness or weakness, trouble sleeping

Joint, muscle or bone aches and pains

Tingling or numbness

Changes in taste, sore throat, cough

Flushing

Stomach upset

Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • You will need regular blood tests while taking ritonavir to check if it is causing problems with your liver or kidneys. You will also need blood tests to check your viral load.
  • As your HIV comes under control, your immune system begins to recover. It may start fighting infections better than before which may make you unwell for a while. Your doctor may call this Immune Reconstitution Syndrome.
  • Treatment for HIV may change your body shape. These changes can include fat build-up, fat loss, or both. Discuss this with your doctor.
  • Do not stop taking ritonavir without talking to your doctor first.