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What does it do?

Evolocumab is used to lower cholesterol. This reduces your chance of having a stroke, heart attack, and other related problems.

Before you start

  • Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

How should you use it?

Inject evolocumab under the skin regularly as directed, usually in the stomach, thigh or upper arm.
To make the injection more comfortable, you can take it out of the fridge at least 30 minutes before you inject it. Choose a new place to inject each time so that you do not become sore in one area.
You, or the person giving the injections, will be given training on how to use them. Click here for a video on how to use evolocumab.

What if you forget a dose?

Inject the missed dose as soon as you remember, then continue a new schedule from that day.

Can you take other medicines?

Tell your pharmacist or doctor about all medicines or treatments that you may be taking, including vitamins, herbal products or recreational drugs.

What side effects might you notice?

Side EffectsRecommended action

Irritation or pain at injection site

Tell your doctor if troublesome

If you notice any other effects, discuss them with your doctor or pharmacist.

Other information:

  • Keep evolocumab in the fridge. You can store it at room temperature for up to 30 days after you take it out of the fridge. Keep it in the box to protect from light.
  • Evolocumab is not registered for use in New Zealand. Discuss with your doctor.

This leaflet contains important, but not all, information about this medicine.

Prepared by the MyMedicines Committee at Christchurch Hospital, Te Whatu Ora - Waitaha, New Zealand. January 2026

For more general information about this sheet and its contents, see: What does a My Medicines sheet cover?

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About My Medicines

My Medicines Patient Information Leaflets (PILs) contain important, but not all, information about the medicines they describe.

For more information about the sheets, see: What does a My Medicines sheet cover?

My Medicines is developed by a team at Te Whatu Ora – Waitaha. Our team is made up of doctors, pharmacists, and a non-medical person to help us keep to plain language. We also discuss our information with specialist health professionals or groups when needed